The Mu - Opioid Receptor Agonist DAMGO Presynaptically Suppresses 3 Solitary Tract - Evoked Input to Neurons in the 4 Rostral Solitary
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چکیده
2 The Mu-Opioid Receptor Agonist DAMGO Presynaptically Suppresses 3 Solitary Tract-Evoked Input to Neurons in the 4 Rostral Solitary Nucleus 5 6 Alison J. Boxwell, Yuchio Yanagawa, Susan P. Travers, Joseph B. Travers 7 8 Division of Oral Biology, College of Dentistry 9 The Ohio State University 10 305 W 12th Ave 11 Columbus OH 43210 12 2 Neuroscience Graduate Studies Program 13 The Ohio State University 14 333 W 10 Ave 15 Columbus OH 43210 16 Department of Genetic and Behavioral Neuroscience, 17 Gunma University Graduate School of Medicine and Japan Science and Technology 18 Agency, CREST, 3-39-22 Showa-machi, Maebashi 371-8511, Japan 19 20 21 Running Head: DAMGO suppresses ST-evoked input 22 23 31 pages 24 6 figures 25 1 Table 26 27 Correspondence to: 28 Alison Boxwell 29 College of Dentistry 30 305 W 12th Ave 31 Articles in PresS. J Neurophysiol (March 13, 2013). doi:10.1152/jn.00711.2012
منابع مشابه
The μ-opioid receptor agonist DAMGO presynaptically suppresses solitary tract-evoked input to neurons in the rostral solitary nucleus.
Taste processing in the rostral nucleus of the solitary tract (rNST) is subject to modulatory influences including opioid peptides. Behavioral pharmacological studies suggest an influence of μ-opioid receptors in rNST, but the underlying mechanism is unknown. To determine the cellular site of action, we tested the effects of the μ-opioid receptor agonist DAMGO in vitro. Whole cell patch-clamp r...
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